Colitis in a transgenic mouse model of autoimmune uveitis may be induced by neoantigen presentation in the bowel

Abstract Undifferentiated uveitis (intraocular inflammation, IOI) is an idiopathic sight-threatening, presumed autoimmune disease, accountable for ~ 10% of all blindness in the developed world. We have investigated the association of uveitis with inflammatory bowel disease (IBD) using a mouse model...

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Bibliographic Details
Main Authors: C. Mölzer, Y.-H. Liu, E. Muckersie, I. P. Klaska, R. Cornall, H. M. Wilson, L. Kuffová, J. V. Forrester
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-27018-9