TP53 Alterations in Myelodysplastic Syndromes and Acute Myeloid Leukemia
TP53 mutations are less frequent in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) than in solid tumors, except in secondary and therapy-related MDS/AMLs, and in cases with complex monosomal karyotype. As in solid tumors, missense mutations predominate, with the same hotspot mutate...
| Hlavní autoři: | , , , |
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| Médium: | Článek |
| Jazyk: | English |
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MDPI AG
2023-04-01
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| Edice: | Biomedicines |
| Témata: | |
| On-line přístup: | https://www.mdpi.com/2227-9059/11/4/1152 |