TP53 Alterations in Myelodysplastic Syndromes and Acute Myeloid Leukemia

TP53 mutations are less frequent in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) than in solid tumors, except in secondary and therapy-related MDS/AMLs, and in cases with complex monosomal karyotype. As in solid tumors, missense mutations predominate, with the same hotspot mutate...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Ramy Rahmé, Thorsten Braun, James J. Manfredi, Pierre Fenaux
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: MDPI AG 2023-04-01
Sraith:Biomedicines
Ábhair:
Rochtain ar líne:https://www.mdpi.com/2227-9059/11/4/1152