TP53 Alterations in Myelodysplastic Syndromes and Acute Myeloid Leukemia

TP53 Alterations in Myelodysplastic Syndromes and Acute Myeloid Leukemia

TP53 mutations are less frequent in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) than in solid tumors, except in secondary and therapy-related MDS/AMLs, and in cases with complex monosomal karyotype. As in solid tumors, missense mutations predominate, with the same hotspot mutate...

Bibliográfalaš dieđut
Váldodahkkit:	Ramy Rahmé, Thorsten Braun, James J. Manfredi, Pierre Fenaux
Materiálatiipa:	Artihkal
Giella:	English
Almmustuhtton:	MDPI AG 2023-04-01
Ráidu:	Biomedicines
Fáttát:	mutant p53 cancer myelodysplasia acute myeloid leukemia
Liŋkkat:	https://www.mdpi.com/2227-9059/11/4/1152

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