Amyloid beta and Alzheimer’s Disease: The role of neprilysin-2 in amyloid-beta clearance
Accumulation of the amyloid-beta (Ab) peptide is a central factor in Alzheimer’s disease (AD) pathogenesis as supported by continuing evidence. This review concisely summarizes this evidence supporting a critical role for Ab in AD before discussing the clearance of this peptide. Mechanisms of cleara...
| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
Frontiers Media S.A.
2014-08-01
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| coleção: | Frontiers in Aging Neuroscience |
| Assuntos: | |
| Acesso em linha: | http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00187/full |