Antitumor and apoptotic effects of bergaptol are mediated via mitochondrial death pathway and cell cycle arrest in human breast carcinoma cells

The aim of the present research work was to investigate the anti-cancer and apoptotic effects of bergaptol in human breast cancer cells (MCF-7). The effects on cell cycle arrest and caspase activation were evaluated. MTT assay was used to evaluate the effect of the compound on cell viability. Cellul...

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Bibliographic Details
Main Authors: Zhi-Cheng Ge, Xiang Qu, He-Fen Yu, Hui-Ming Zhang, Zi-Han Wang, Zhong-Tao Zhang
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2016-04-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Online Access:https://www.banglajol.info/index.php/BJP/article/view/24644