Propafenone HCl fast dissolving tablets containing subliming agent prepared by direct compression method

Propafenone HCl (PPH), an antiarrhythmic drug, has a bitter taste, short half-life, delayed drug dissolution and side effects. Thus, the purpose of this work is to develop orally fast dissolving tablets (OFDTs) containing PPH to provide a rapid drug dissolution and subsequently give rapid onset of a...

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Bibliographic Details
Main Authors: Saleh Abd El Rasoul, Gamal A. Shazly
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Saudi Pharmaceutical Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S131901641730110X