Evaluation of intracellular signal molecules that regulate TLR4-stimulated inflammatory mediator expression in cultured rat chondrocytes

Osteoarthritis (OA) is characterized by inflammation of joints and degradation of articular cartilage matrix. As involvement of damage-associated molecular patterns (DAMPs) in the pathogenesis of OA has been reported, the present study comprehensively investigated the regulation of inflammatory medi...

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Bibliographic Details
Main Authors: Hiroki Hashizume, Hatsune Motonari, Yoki Nakamura, Kazue Hisaoka-Nakashima, Norimitsu Morioka
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861323000208