Beta Cell Physiological Dynamics and Dysfunctional Transitions in Response to Islet Inflammation in Obesity and Diabetes
Beta cells adapt their function to respond to fluctuating glucose concentrations and variable insulin demand. The highly specialized beta cells have well-established endoplasmic reticulum to handle their high metabolic load for insulin biosynthesis and secretion. Beta cell endoplasmic reticulum ther...
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Format: | Article |
Language: | English |
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MDPI AG
2020-11-01
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Series: | Metabolites |
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Online Access: | https://www.mdpi.com/2218-1989/10/11/452 |