Beta Cell Physiological Dynamics and Dysfunctional Transitions in Response to Islet Inflammation in Obesity and Diabetes

Beta cells adapt their function to respond to fluctuating glucose concentrations and variable insulin demand. The highly specialized beta cells have well-established endoplasmic reticulum to handle their high metabolic load for insulin biosynthesis and secretion. Beta cell endoplasmic reticulum ther...

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Bibliographic Details
Main Author: Marlon E. Cerf
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/10/11/452