HOXB7 accelerates the malignant progression of hepatocellular carcinoma by promoting stemness and epithelial-mesenchymal transition

HOXB7 accelerates the malignant progression of hepatocellular carcinoma by promoting stemness and epithelial-mesenchymal transition

Abstract Background Homeobox B7 (HOXB7) has been identified associated with poor prognosis of hepatocellular carcinoma (HCC). However, the specific mechanism by which HOXB7 promotes the malignant progression of HCC remains to be determined. Methods Immunohistochemistry (IHC) was used to detect the e...

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Bibliographic Details
Main Authors: Hong-bo Huan, Da-peng Yang, Xu-dong Wen, Xue-jiao Chen, Liang Zhang, Li-li Wu, Ping Bie, Feng Xia
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Hepatocellular carcinoma
Homeobox B7
Stemness
Epithelial-mesenchymal transition
c-Myc
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Online Access:http://link.springer.com/article/10.1186/s13046-017-0559-4

Internet

http://link.springer.com/article/10.1186/s13046-017-0559-4

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