Female Rats Are Resistant to Cognitive, Motor and Dopaminergic Deficits in the Reserpine-Induced Progressive Model of Parkinson’s Disease

Female Rats Are Resistant to Cognitive, Motor and Dopaminergic Deficits in the Reserpine-Induced Progressive Model of Parkinson’s Disease

Parkinson’s disease (PD) is the second most common neurodegenerative disease. The main symptoms are motor signs such as resting tremor and difficulty in initializing movements. Non-motor alterations, such as cognitive deficits, can precede the motor symptoms. PD is more frequent in men than women. T...

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Bibliographic Details
Main Authors: Alvaro C. Lima, Ywlliane S. R. Meurer, Vinicius S. Bioni, Débora M. G. Cunha, Narriman Gonçalves, Leonardo B. Lopes-Silva, Marcela Becegato, Manuela B. L. Soares, Gabriela F. Marinho, José R. Santos, Regina H. Silva
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
parkinsonism
motor impairment
cognitive deficits
sexual dimorphism
tyrosine hydroxylase
estrogen
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.757714/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2021.757714/full

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