Pharmacokinetics and thermal anti-nociceptive effects of oral morphine in horses

IntroductionMorphine is an effective analgesic in horses, however, IV administration at therapeutic doses has been shown to produce dose-dependent neuroexcitation and unwanted gastrointestinal effects. The analgesic effects of morphine have, at least in part, been attributed to the morphine-6-glucur...

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Bibliographic Details
Main Authors: Heather K. Knych, Stacy J. Steinmetz, Megan L. Traynham, Daniel S. McKemie, Philip H. Kass
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
Series:Frontiers in Veterinary Science
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2024.1461648/full