Knockdown of the bovine prion gene PRNP by RNA interference (RNAi) technology

<p>Abstract</p> <p>Background</p> <p>Since prion gene-knockout mice do not contract prion diseases and animals in which production of prion protein (PrP) is reduced by half are resistant to the disease, we hypothesized that bovine animals with reduced PrP would be toler...

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Detaylı Bibliyografya
Asıl Yazarlar: Wongsrikeao Pimprapar, Kudo Toshiyuki, Kunishi Miho, Sutou Shizuyo, Miyagishi Makoto, Otoi Takeshige
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: BMC 2007-07-01
Seri Bilgileri:BMC Biotechnology
Online Erişim:http://www.biomedcentral.com/1472-6750/7/44