Transcription-dependent silencing of inducible convergent transgenes in transgenic mice

<p>Abstract</p> <p>Background</p> <p>Silencing of transgenes in mice is a common phenomenon typically associated with short multi-copy transgenes. We have investigated the regulation of the highly inducible human granulocyte-macrophage colony-stimulating-factor gene <...

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Bibliographic Details
Main Authors: Calero-Nieto Fernando J, Bert Andrew G, Cockerill Peter N
Format: Article
Language:English
Published: BMC 2010-01-01
Series:Epigenetics & Chromatin
Online Access:http://www.epigeneticsandchromatin.com/content/3/1/3