Formulation and Optimization of Alogliptin-Loaded Polymeric Nanoparticles: In Vitro to In Vivo Assessment

Formulation and Optimization of Alogliptin-Loaded Polymeric Nanoparticles: In Vitro to In Vivo Assessment

The nano-drug delivery system has gained greater acceptability for poorly soluble drugs. Alogliptin (ALG) is a FDA-approved oral anti-hyperglycemic drug that inhibits dipeptidyl peptidase-4. The present study is designed to prepare polymeric ALG nanoparticles (NPs) for the management of diabetes. AL...

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Bibliographic Details
Main Authors: Dibyalochan Mohanty, Sadaf Jamal Gilani, Ameeduzzafar Zafar, Syed Sarim Imam, Ladi Alik Kumar, Mohammed Muqtader Ahmed, Mohammed Asadullah Jahangir, Vasudha Bakshi, Wasim Ahmad, Eyman Mohamed Eltayib
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Molecules
Subjects:
alogliptin
nanoparticle
Eudragit
pharmacokinetic study
antidiabetic activity
Online Access:https://www.mdpi.com/1420-3049/27/14/4470

Internet

https://www.mdpi.com/1420-3049/27/14/4470

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