The role of endothelin-1 in the doxorubicin cardiotoxicity
Background: The cardiotoxicity of doxorubicin (Dx), an antineoplastic drug, is imposed by the development of cardiomyopathy and heart failure. The expression of endothelin-1 (ET-1) in myocardium under the action of Dx, directly correlates with the degree of cardiac dysfunction, mediated by endothe...
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Format: | Article |
Language: | English |
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Scientific Medical Association of Moldova
2020-10-01
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Series: | The Moldovan Medical Journal |
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Online Access: | http://moldmedjournal.md/wp-content/uploads/2020/09/moldovan-med-j-2020-63-4-tacu-full-text.pdf |