Chromatin network retards nucleoli coalescence
Nuclear bodies are membraneless condensates that may form via liquid-liquid phase separation; however, they defy theoretical predictions where the equilibrium state should consist of a single droplet. Here the authors use a diploid human genome model parameterized with Hi-C data to simulate nucleoli...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-27123-9 |