nnSVG for the scalable identification of spatially variable genes using nearest-neighbor Gaussian processes

Abstract Feature selection to identify spatially variable genes or other biologically informative genes is a key step during analyses of spatially-resolved transcriptomics data. Here, we propose nnSVG, a scalable approach to identify spatially variable genes based on nearest-neighbor Gaussian proces...

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Bibliographic Details
Main Authors: Lukas M. Weber, Arkajyoti Saha, Abhirup Datta, Kasper D. Hansen, Stephanie C. Hicks
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39748-z