Lung cancer induced in mice by the envelope protein of jaagsiekte sheep retrovirus (JSRV) closely resembles lung cancer in sheep infected with JSRV

<p>Abstract</p> <p>Background</p> <p>Jaagsiekte sheep retrovirus (JSRV) causes a lethal lung cancer in sheep and goats. Expression of the JSRV envelope (Env) protein in mouse lung, by using a replication-defective adeno-associated virus type 6 (AAV6) vector, induces tum...

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Bibliographic Details
Main Authors: York Denis, Alpers Charles E, Hudkins Kelly L, Metzger Michael J, Wootton Sarah K, DeMartini James C, Miller A Dusty
Format: Article
Language:English
Published: BMC 2006-12-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/3/1/94