Density dependent regulation of inflammatory responses in macrophages

Density dependent regulation of inflammatory responses in macrophages

Macrophage distribution density is tightly regulated within the body, yet the importance of macrophage crowding during in vitro culture is largely unstudied. Using a human induced pluripotent stem cell (iPSC)-derived macrophage model of tissue resident macrophages, we characterize how increasing mac...

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Bibliographic Details
Main Authors: Alun Vaughan-Jackson, Szymon Stodolak, Kourosh H. Ebrahimi, Errin Johnson, Paul K. Reardon, Maeva Dupont, Shengpan Zhang, James S. O. McCullagh, William S. James
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
macrophage
stem cell
inflammation
density
differentiation
microglia
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.895488/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.895488/full

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