Erythroid SLC7A5/SLC3A2 amino acid carrier controls red blood cell size and maturation

Erythroid SLC7A5/SLC3A2 amino acid carrier controls red blood cell size and maturation

Summary: Inhibition of the heterodimeric amino acid carrier SLC7A5/SLC3A2 (LAT1/CD98) has been widely studied in tumor biology but its role in physiological conditions remains largely unknown. Here we show that the SLC7A5/SLC3A2 heterodimer is constitutively present at different stages of erythroid...

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Bibliographic Details
Main Authors: Antonio Bouthelier, Lucía Fernández-Arroyo, Claudia Mesa-Ciller, Danay Cibrian, Noa Beatriz Martín-Cófreces, Raquel Castillo-González, Macarena Calero, Diego Herráez-Aguilar, Andrea Guajardo-Grence, Ana María Pacheco, Ana Marcos-Jiménez, Borja Quiroga, Marta Morado, Francisco Monroy, Cecilia Muñoz-Calleja, Francisco Sánchez-Madrid, Andrés A. Urrutia, Julián Aragonés
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:iScience
Subjects:
Molecular physiology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222020120

Internet

http://www.sciencedirect.com/science/article/pii/S2589004222020120

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