Fear and reward circuit alterations in pediatric CRPS

Fear and reward circuit alterations in pediatric CRPS

In chronic pain, a number of brain regions involved in emotion (e.g., amygdala, hippocampus, nucleus accumbens, insula, anterior cingulate, and prefrontal cortex) show significant functional and morphometric changes. One phenotypic manifestation of these changes is pain-related fear (PRF). PRF is as...

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Bibliographic Details
Main Authors: Laura E Simons, Nathalie eErpelding, Jessica eHernandez, Paul eSerrano, Kunyu eZhang, Alyssa eLebel, Navil eSethna, Charles eBerde, Sanjay ePrabhu, Lino eBecerra, David eBorsook
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Human Neuroscience
Subjects:
Amygdala
Chronic Pain
Putamen
fMRI
functional imaging
Children
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnhum.2015.00703/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnhum.2015.00703/full

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