Modafinil as a catecholaminergic agent: empirical evidence and unanswered questions

Modafinil, in its two clinical formulations (Provigil® and Nuvigil®), is a widely prescribed wake-promoting therapeutic agent. It binds competitively to the cell membrane dopamine transporter and is dependent on catecholaminergic (dopaminergic and adrenergic) signaling for its wake...

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Bibliographic Details
Main Author: Jonathan P Wisor
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Neurology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00139/full