NetTCR-2.1: Lessons and guidance on how to develop models for TCR specificity predictions

NetTCR-2.1: Lessons and guidance on how to develop models for TCR specificity predictions

T cell receptors (TCR) define the specificity of T cells and are responsible for their interaction with peptide antigen targets presented in complex with major histocompatibility complex (MHC) molecules. Understanding the rules underlying this interaction hence forms the foundation for our understan...

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Bibliographic Details
Main Authors: Alessandro Montemurro, Leon Eyrich Jessen, Morten Nielsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
T cell
epitope
deep learning
TCR specificity
neural network
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1055151/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1055151/full

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