Association between plasma somatic copy number variations and response to immunotherapy in patients with programmed death-ligand 1-negative non-small cell lung cancer

Association between plasma somatic copy number variations and response to immunotherapy in patients with programmed death-ligand 1-negative non-small cell lung cancer

Objective To determine how patients with non-small cell lung cancer (NSCLC) with programmed death-ligand 1 (PD-L1)-negative and/or a low tumor mutation burden status benefit from immune checkpoint inhibitors (ICI). Methods We determined the plasma cell-free DNA profiles of 25 patients with PD-L1-neg...

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Bibliographic Details
Main Authors: Xiaochen Zhang, Yina Wang, Jingjing Xiang, Pan Zhao, Yanping Xun, Shirong Zhang, Nong Xu
Format: Article
Language:English
Published: SAGE Publishing 2022-04-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605221093222

Internet

https://doi.org/10.1177/03000605221093222

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