The atypical sphingolipid SPB 18:1(14Z);O2 is a biomarker for DEGS1 related hypomyelinating leukodystrophy

The atypical sphingolipid SPB 18:1(14Z);O2 is a biomarker for DEGS1 related hypomyelinating leukodystrophy

Sphingolipids (SL) represent a structurally diverse class of lipids that are central to cellular physiology and neuronal development and function. Defects in the sphingolipid metabolism are typically associated with nervous system disorders. The C4-dihydroceramide desaturase (DEGS1) catalyzes the co...

Full description

Bibliographic Details
Main Authors: Andreas J. Hülsmeier, Sandra P. Toelle, Peter Bellstedt, Christian Wentzel, Angela Bahr, Konstantinos Kolokotronis, Thorsten Hornemann
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Journal of Lipid Research
Subjects:
Sphingolipids
DEGS1
hypomyelinating leukodystrophy
sphingolipidosis
HLD18
biomarker
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227523001372

Internet

http://www.sciencedirect.com/science/article/pii/S0022227523001372

Similar Items