Disulfiram Overcomes Cisplatin Resistance in Human Embryonal Carcinoma Cells

Disulfiram Overcomes Cisplatin Resistance in Human Embryonal Carcinoma Cells

Cisplatin resistance in testicular germ cell tumors (TGCTs) is a clinical challenge. We investigated the underlying mechanisms associated with cancer stem cell (CSC) markers and modalities circumventing the chemoresistance. Chemoresistant models (designated as CisR) of human embryonal carcinoma cell...

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Bibliographic Details
Main Authors: Silvia Schmidtova, Katarina Kalavska, Katarina Gercakova, Zuzana Cierna, Svetlana Miklikova, Bozena Smolkova, Verona Buocikova, Viera Miskovska, Erika Durinikova, Monika Burikova, Michal Chovanec, Miroslava Matuskova, Michal Mego, Lucia Kucerova
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
testicular germ cell tumors
embryonal carcinoma
chemoresistance
cisplatin
cancer stem cell markers
Online Access:https://www.mdpi.com/2072-6694/11/9/1224

Internet

https://www.mdpi.com/2072-6694/11/9/1224

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