Heterogeneous absorption of antimicrobial peptide LL37 in Escherichia coli cells enhances population survivability

Heterogeneous absorption of antimicrobial peptide LL37 in Escherichia coli cells enhances population survivability

Antimicrobial peptides (AMPs) are broad spectrum antibiotics that selectively target bacteria. Here we investigate the activity of human AMP LL37 against Escherichia coli by integrating quantitative, population and single-cell level experiments with theoretical modeling. We observe an unexpected, ra...

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Bibliographic Details
Main Authors: Mehdi Snoussi, John Paul Talledo, Nathan-Alexander Del Rosario, Salimeh Mohammadi, Bae-Yeun Ha, Andrej Košmrlj, Sattar Taheri-Araghi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-12-01
Series:eLife
Subjects:
antimicrobial peptides
minimum inhibitory concentration
inoculum effect
population dynamics
peptide absorption
Online Access:https://elifesciences.org/articles/38174

Internet

https://elifesciences.org/articles/38174

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