Conversion of Natural Narciclasine to Its C-1 and C-6 Derivatives and Their Antitumor Activity Evaluation: Some Unusual Chemistry of Narciclasine

During the search for a general, efficient route toward the synthesis of C-1 analogues of narciclasine, natural narciclasine was protected and converted to its C-1 enol derivative using a novel semi-synthetic route. Attempted conversion of this material to its triflate in order to conduct cross-coup...

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Bibliographic Details
Main Authors: Juana Goulart Stollmaier, Jared Thomson, Mary Ann Endoma-Arias, Razvan Simionescu, Alexandra Vernaza, Nakya Mesa-Diaz, Mitchell Smith, Liqin Du, Alexander Kornienko, Tomas Hudlicky
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/13/4141