Routine Clinically Detected Increased ROS1 Transcripts Are Related With ROS1 Expression by Immunohistochemistry and Associated With EGFR Mutations in Lung Adenocarcinoma

Routine Clinically Detected Increased ROS1 Transcripts Are Related With ROS1 Expression by Immunohistochemistry and Associated With EGFR Mutations in Lung Adenocarcinoma

Introduction: Translocations of the ROS1 gene were found to drive tumorigenesis in 1% to 2% of lung adenocarcinoma. In clinical practice, ROS1 rearrangements are often screened by immunohistochemistry (IHC) before confirmation with either fluorescence in situ hybridization or molecular techniques. T...

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Bibliographic Details
Main Authors: Karl Grenier, MD, PhD, Jean-Baptiste Rivière, PhD, Bouchra Ouled Amar Bencheikh, PhD, Andrea Liliam Gomez Corredor, PhD, Benjamin Christopher Shieh, MD, Hangjun Wang, MD, Pierre Olivier Fiset, MD, PhD, Sophie Camilleri-Broët, MD, PhD
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:JTO Clinical and Research Reports
Subjects:
ROS1
NSCLC
Lung adenocarcinoma
EGFR
Biomarker
Immunohistochemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S2666364323000693

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http://www.sciencedirect.com/science/article/pii/S2666364323000693

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