Application of high-throughput sequencing technology in HIV drug resistance detection

Drug resistance via drug-resistant mutations in the human immunodeficiency virus (HIV) genome is the primary cause of antiviral therapy failure. Consequently, HIV drug resistance genotyping has become a critical approach in HIV prevention and control. Compared to the Sanger sequencing technology, hi...

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Bibliographic Details
Main Authors: Yuanyuan Zhang, Liying Ma
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Biosafety and Health
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590053621000628