PPARdelta in Affected Atopic Dermatitis and Psoriasis: A Possible Role in Metabolic Reprograming

PPARdelta in Affected Atopic Dermatitis and Psoriasis: A Possible Role in Metabolic Reprograming

Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors expressed in the skin. Three PPAR isotypes, α (NRC1C1), β or δ (NRC1C2) and γ (NRC1C3), have been identified. After activation through ligand binding, PPARs heterodimerize with the 9-cis-retinoic acid receptor (RXR), a...

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Bibliographic Details
Main Authors: Stefan Blunder, Petra Pavel, Deborah Minzaghi, Sandrine Dubrac
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
PPAR
atopic dermatitis
psoriasis
metabolic reprograming
glucose
fatty acids
Online Access:https://www.mdpi.com/1422-0067/22/14/7354

Internet

https://www.mdpi.com/1422-0067/22/14/7354

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