Protein Dynamics in F-like Bacterial Conjugation

Protein Dynamics in F-like Bacterial Conjugation

Efficient in silico development of novel antibiotics requires high-resolution, dynamic models of drug targets. As conjugation is considered the prominent contributor to the spread of antibiotic resistance genes, targeted drug design to disrupt vital components of conjugative systems has been propose...

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Bibliographic Details
Main Authors: Nicholas Bragagnolo, Christina Rodriguez, Naveed Samari-Kermani, Alice Fours, Mahboubeh Korouzhdehi, Rachel Lysenko, Gerald F. Audette
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biomedicines
Subjects:
bacterial conjugation
type IV secretion system (T4SS)
F plasmid
pilus protein structure
protein dynamics
protein-protein interactions
Online Access:https://www.mdpi.com/2227-9059/8/9/362

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https://www.mdpi.com/2227-9059/8/9/362

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