Long-Term Modeling of SARS-CoV-2 Infection of <italic toggle="yes">In Vitro</italic> Cultured Polarized Human Airway Epithelium

Long-Term Modeling of SARS-CoV-2 Infection of <italic toggle="yes">In Vitro</italic> Cultured Polarized Human Airway Epithelium

ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replicates throughout human airways. The polarized human airway epithelium (HAE) cultured at an airway-liquid interface (HAE-ALI) is an in vitro model mimicking the in vivo human mucociliary airway epithelium and supports the repl...

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Bibliographic Details
Main Authors: Siyuan Hao, Kang Ning, Cagla Aksu Kuz, Kai Vorhies, Ziying Yan, Jianming Qiu
Format: Article
Language:English
Published: American Society for Microbiology 2020-12-01
Series:mBio
Subjects:
SARS-CoV-2
human airway epithelium
epithelial damage
recurrent infection
airway epithelial damage
long-term infection
Online Access:https://journals.asm.org/doi/10.1128/mBio.02852-20

Internet

https://journals.asm.org/doi/10.1128/mBio.02852-20

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