Segmentation and classification of two-channel C. elegans nucleus-labeled fluorescence images

Segmentation and classification of two-channel C. elegans nucleus-labeled fluorescence images

Abstract Background Aging is characterized by a gradual breakdown of cellular structures. Nuclear abnormality is a hallmark of progeria in human. Analysis of age-dependent nuclear morphological changes in Caenorhabditis elegans is of great value to aging research, and this calls for an automatic ima...

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Bibliographic Details
Main Authors: Mengdi Zhao, Jie An, Haiwen Li, Jiazhi Zhang, Shang-Tong Li, Xue-Mei Li, Meng-Qiu Dong, Heng Mao, Louis Tao
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Bioinformatics
Subjects:
C. elegans
Nucleus
Aging
Two-channel fluorescence image
Morphology
Segmentation
Online Access:http://link.springer.com/article/10.1186/s12859-017-1817-3

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http://link.springer.com/article/10.1186/s12859-017-1817-3

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