Evaluating the therapeutic role of selected active compounds in Plumula Nelumbinis on pulmonary hypertension via network pharmacology and experimental analysis

Evaluating the therapeutic role of selected active compounds in Plumula Nelumbinis on pulmonary hypertension via network pharmacology and experimental analysis

Excessive proliferation and migration of pulmonary artery smooth muscle cells (PASMCs) are critical factors leading to vascular remodeling in pulmonary hypertension (PH). This study aimed to explore the effect and potential mechanism of Plumula Nelumbinis on PH by using network pharmacology and expe...

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Bibliographic Details
Main Authors: Xinghua Xiao, Fangmei Luo, Minyi Fu, Yueping Jiang, Shao Liu, Bin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
pulmonary hypertension
network pharmacology
Plumula Nelumbinis
alkaloids
PASMCs proliferation
PASMCs migration
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.977921/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.977921/full

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