Cytokine receptor-Eb1 interaction couples cell polarity and fate during asymmetric cell division

Asymmetric stem cell division is a critical mechanism for balancing self-renewal and differentiation. Adult stem cells often orient their mitotic spindle to place one daughter inside the niche and the other outside of it to achieve asymmetric division. It remains unknown whether and how the niche ma...

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Bibliographic Details
Main Authors: Cuie Chen, Ryan Cummings, Aghapi Mordovanakis, Alan J Hunt, Michael Mayer, David Sept, Yukiko M Yamashita
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/33685