Looking for therapeutic antibodies in next-generation sequencing repositories

Recently it has become possible to query the great diversity of natural antibody repertoires using next-generation sequencing (NGS). These methods are capable of producing millions of sequences in a single experiment. Here we compare clinical-stage therapeutic antibodies to the ~1b sequences from 60...

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Dettagli Bibliografici
Autori principali: Konrad Krawczyk, Matthew I. J. Raybould, Aleksandr Kovaltsuk, Charlotte M. Deane
Natura: Articolo
Lingua:English
Pubblicazione: Taylor & Francis Group 2019-10-01
Serie:mAbs
Soggetti:
Accesso online:https://www.tandfonline.com/doi/10.1080/19420862.2019.1633884