Swainsonine represses glioma cell proliferation, migration and invasion by reduction of miR-92a expression

Swainsonine represses glioma cell proliferation, migration and invasion by reduction of miR-92a expression

Abstract Background Swainsonine is a natural indolizidine alkaloid, its anti-tumor activity has been widely reported in varied cancers. This study aimed to investigate whether Swainsonine exerted anti-tumor impact on glioma cells, likewise uncovered the relative molecular mechanisms. Methods After a...

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Bibliographic Details
Main Authors: Libo Sun, Xingyi Jin, Lijuan Xie, Guangjun Xu, Yunxia Cui, Zhuo Chen
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Cancer
Subjects:
Swainsonine
microRNA-92a
Glioma
Proliferation
PI3K/AKT/mTOR
Online Access:http://link.springer.com/article/10.1186/s12885-019-5425-7

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http://link.springer.com/article/10.1186/s12885-019-5425-7

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