Activation of astrocytes in the basal forebrain in mice facilitates isoflurane-induced loss of consciousness and prolongs recovery

Activation of astrocytes in the basal forebrain in mice facilitates isoflurane-induced loss of consciousness and prolongs recovery

Abstract Objectives General anesthesia results in a state of unconsciousness that is similar to sleep. In recent years, increasing evidence has reported that astrocytes play a crucial role in regulating sleep. However, whether astrocytes are involved in general anesthesia is unknown. Methods In the...

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Bibliographic Details
Main Authors: Jialing Lin, Xuefeng Cheng, Haoyuan Wang, Lin Du, Xiangyu Li, Gaofeng Zhao, Chuangbo Xie
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Anesthesiology
Subjects:
Basal forebrain
Astrocyte
DREADDs
Isoflurane anesthesia
Online Access:https://doi.org/10.1186/s12871-023-02166-1

Internet

https://doi.org/10.1186/s12871-023-02166-1

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