Evolutionary activation of acidic chitinase in herbivores through the H128R mutation in ruminant livestock

Summary: Placental mammals' ancestors were insectivores, suggesting that modern mammals may have inherited the ability to digest insects. Acidic chitinase (Chia) is a crucial enzyme hydrolyzing significant component of insects' exoskeleton in many species. On the other hand, herbivorous an...

Full description

Bibliographic Details
Main Authors: Eri Tabata, Ikuto Kobayashi, Takuya Morikawa, Akinori Kashimura, Peter O. Bauer, Fumitaka Oyama
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223013317