Blood Flow and Glucose Metabolism Dissociation in the Putamen Is Predictive of Levodopa Induced Dyskinesia in Parkinson's Disease Patients

Blood Flow and Glucose Metabolism Dissociation in the Putamen Is Predictive of Levodopa Induced Dyskinesia in Parkinson's Disease Patients

Background: The forefront treatment of Parkinson's disease (PD) is Levodopa. When patients are treated with Levodopa cerebral blood flow is increased while cerebral metabolic rate is decreased in key subcortical regions including the putamen. This phenomenon is especially pronounced in patients...

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Bibliographic Details
Main Authors: Maram Aljuaid, Samuel Booth, Douglas E. Hobson, Andrew Borys, Kelly Williams, Audrey Katako, Lawrence Ryner, Andrew L. Goertzen, Ji Hyun Ko
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Neurology
Subjects:
cerebral blood flow
glucose metabolism
magnetic resonance imaging
neurovascular coupling hypothesis
positron emission tomography
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01217/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.01217/full

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