Long-Term Calorie Restriction Alters Anxiety-like Behaviour and the Brain and Adrenal Gland Transcriptomes of the Ageing Male Rat

Further examination of the molecular regulators of long-term calorie restriction (CR), reported to have an anxiolytic effect, may highlight novel therapeutic targets for anxiety disorders. Here, adult male Hooded Wistar rats were exposed to a 25% CR whilst anxiety-like behaviour was assessed at 6-,...

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Bibliographic Details
Main Authors: Antonina Govic, Helen Nasser, Elizabeth A. Levay, Matt Zelko, Esmaeil Ebrahimie, Manijeh Mohammadi Dehcheshmeh, Stephen Kent, Jim Penman, Agnes Hazi
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/14/21/4670