Effects of intratracheal administration of nuclear factor-kappaB decoy oligodeoxynucleotides on long-term cigarette smoke-induced lung inflammation and pathology in mice

<p>Abstract</p> <p>To determine if nuclear factor-κB (NF-κB) activation may be a key factor in lung inflammation and respiratory dysfunction, we investigated whether NF-κB can be blocked by intratracheal administration of NF-κB decoy oligodeoxynucleotides (ODNs), and whether decoy...

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Bibliographic Details
Main Authors: Wang Yu-Zhu, He Bei, Li Yu-Tao, Wang Jing
Format: Article
Language:English
Published: BMC 2009-08-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/10/1/79