hiPSC-derived cardiomyocytes as a model to study the role of small-conductance Ca2+-activated K+ (SK) ion channel variants associated with atrial fibrillation

hiPSC-derived cardiomyocytes as a model to study the role of small-conductance Ca2+-activated K+ (SK) ion channel variants associated with atrial fibrillation

Atrial fibrillation (AF), the most common arrhythmia, has been associated with different electrophysiological, molecular, and structural alterations in atrial cardiomyocytes. Therefore, more studies are required to elucidate the genetic and molecular basis of AF. Various genome-wide association stud...

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Bibliographic Details
Main Authors: Hosna Babini, Verónica Jiménez-Sábado, Ekaterina Stogova, Alia Arslanova, Mariam Butt, Saif Dababneh, Parisa Asghari, Edwin D. W. Moore, Thomas W. Claydon, Nipavan Chiamvimonvat, Leif Hove-Madsen, Glen F. Tibbits
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
small-conductance Ca2+-activated K+ channels
atrial fibrillation
calcium
cardiac action potential
single nucleotide polymorphisms
human induced pluripotent stem cells
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1298007/full

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https://www.frontiersin.org/articles/10.3389/fcell.2024.1298007/full

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