Dynamical modeling predicts an inflammation-inducible CXCR7+ B cell precursor with potential implications in lymphoid blockage pathologies
Background The blockage at the early B lymphoid cell development pathway within the bone marrow is tightly associated with hematopoietic and immune diseases, where the disruption of basal regulatory networks prevents the continuous replenishment of functional B cells. Dynamic computational models ma...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2020-09-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/9902.pdf |