Dynamical modeling predicts an inflammation-inducible CXCR7+ B cell precursor with potential implications in lymphoid blockage pathologies
Background The blockage at the early B lymphoid cell development pathway within the bone marrow is tightly associated with hematopoietic and immune diseases, where the disruption of basal regulatory networks prevents the continuous replenishment of functional B cells. Dynamic computational models ma...
Main Authors: | Jennifer Enciso, Luis Mendoza, Elena R. Álvarez-Buylla, Rosana Pelayo |
---|---|
Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2020-09-01
|
Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/9902.pdf |
Similar Items
-
Cellular niches for hematopoietic stem cells in bone marrow under normal and malignant conditions
by: Yoshiki Omatsu
Published: (2023-02-01) -
Awakening of Dormant Breast Cancer Cells in the Bone Marrow
by: Robert Wieder
Published: (2023-06-01) -
Total Marrow and Lymphoid Irradiation: A New Technology Assisting in Myeloablating Before Hematopoietic Stem Cell Transplantation
by: SHEN Jing, et al.
Published: (2023-07-01) -
CHARACTERISTICS OF BONE MARROW MICROENVIRONMENT IN MULTIPLE MYELOMA BEFORE AND AFTER TREATMENT
by: V. I. Rugal, et al.
Published: (2019-03-01) -
Of mice and lymphoid aggregates: modeling tertiary lymphoid structures in cancer
by: Alessandra Vaccaro, et al.
Published: (2023-10-01)