Dynamical modeling predicts an inflammation-inducible CXCR7+ B cell precursor with potential implications in lymphoid blockage pathologies

Background The blockage at the early B lymphoid cell development pathway within the bone marrow is tightly associated with hematopoietic and immune diseases, where the disruption of basal regulatory networks prevents the continuous replenishment of functional B cells. Dynamic computational models ma...

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Bibliographic Details
Main Authors: Jennifer Enciso, Luis Mendoza, Elena R. Álvarez-Buylla, Rosana Pelayo
Format: Article
Language:English
Published: PeerJ Inc. 2020-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/9902.pdf

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