The effect of α-tocopherol, α- and γ-tocotrienols on amyloid-β aggregation and disaggregation in vitro

The effect of α-tocopherol, α- and γ-tocotrienols on amyloid-β aggregation and disaggregation in vitro

One of the neuropathological hallmarks of Alzheimer's disease (AD)—causing neurodegeneration and consequent memory deterioration, and eventually, cognitive decline—is amyloid-β (Aβ) aggregation forming amyloid plaques. Our previous study showed the potential of a tocotrienol-rich fraction—a mix...

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Bibliographic Details
Main Authors: Nor Faeizah Ibrahim, Hamizah Shahirah Hamezah, Daijiro Yanagisawa, Mayumi Tsuji, Yuji Kiuchi, Kenjiro Ono, Ikuo Tooyama
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
Amyloid-β
Tocotrienol
Tocopherol
Vitamin E
Alzheimer's disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580821002259

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http://www.sciencedirect.com/science/article/pii/S2405580821002259

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