Association between skeletal muscle mitochondrial dysfunction and insulin resistance in patients with rheumatoid arthritis: a case–control study

Association between skeletal muscle mitochondrial dysfunction and insulin resistance in patients with rheumatoid arthritis: a case–control study

Abstract Background Insulin resistance affects a substantial proportion of patients with rheumatoid arthritis (RA). Skeletal muscle mitochondrial dysfunction results in the accumulation of lipid intermediates that interfere with insulin signaling. We therefore sought to determine if lower oxidative...

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Bibliographic Details
Main Authors: Douglas R. Moellering, Kelley Smith-Johnston, Christian Kelley, Melissa J. Sammy, Jason Benedict, Guy Brock, Jillian Johnson, Kedryn K. Baskin, Wael N. Jarjour, Martha A. Belury, Peter J. Reiser, Prabhakara R. Nagareddy, Beatriz Y. Hanaoka
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Arthritis Research & Therapy
Subjects:
Rheumatoid arthritis
Skeletal muscle
Mitochondria
Online Access:https://doi.org/10.1186/s13075-023-03065-z

Internet

https://doi.org/10.1186/s13075-023-03065-z

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