Impact of Backbone Substitution on Organocatalytic Activity of Sterically Encumbered NHC in Benzoin Condensation

Impact of Backbone Substitution on Organocatalytic Activity of Sterically Encumbered NHC in Benzoin Condensation

In this study, we provide a theoretical explanation for the experimentally observed decrease in the organocatalytic activity of <i>N</i>-aryl imidazolylidenes methylated at the C4/5-H positions in the benzoin condensation of aromatic aldehydes. A comparative quantum chemical study of ene...

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Bibliographic Details
Main Authors: Rinat R. Aysin, Konstantin I. Galkin
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Molecules
Subjects:
benzoin condensation
organocatalysis
<i>N</i>-heterocyclic carbenes
furfural
density functional calculations
Online Access:https://www.mdpi.com/1420-3049/29/8/1704

Internet

https://www.mdpi.com/1420-3049/29/8/1704

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