Crude Saponin from <i>Platycodon grandiflorum</i> Attenuates Aβ-Induced Neurotoxicity via Antioxidant, Anti-Inflammatory and Anti-Apoptotic Signaling Pathways

Crude Saponin from <i>Platycodon grandiflorum</i> Attenuates Aβ-Induced Neurotoxicity via Antioxidant, Anti-Inflammatory and Anti-Apoptotic Signaling Pathways

Although <i>Platycodon grandiflorum</i> saponins exhibit many beneficial biological effects in various diseases and conditions, how they protect nerve cells against neurodegenerative diseases and Alzheimer’s disease (AD) pathology is unknown. We investigated whether <i>P. grandiflo...

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Bibliographic Details
Main Authors: Yun-Jeong Ji, Sujin Kim, Jwa-Jin Kim, Gwi Yeong Jang, Minho Moon, Hyung Don Kim
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Antioxidants
Subjects:
Alzheimer’s disease
antioxidant enzymes
apoptosis
hippocampal neuronal cells
oxidative stress
<i>Platycodon grandiflorum</i> saponin
Online Access:https://www.mdpi.com/2076-3921/10/12/1968

Internet

https://www.mdpi.com/2076-3921/10/12/1968

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